The Authors: Drs Cagle and Allen are authors of numerous books, book chapters and articles on lung and pleural pathology. Dr Cagle is past president of the Pulmonary Pathology Society.
Pathology of the pleura: What the pulmonologists need to know
Article first published online: 30 MAR 2011
© 2011 The Authors. Respirology © 2011 Asian Pacific Society of Respirology
Volume 16, Issue 3, pages 430–438, April 2011
How to Cite
CAGLE, P. T. and ALLEN, T. C. (2011), Pathology of the pleura: What the pulmonologists need to know. Respirology, 16: 430–438. doi: 10.1111/j.1440-1843.2011.01957.x
SERIES EDITORS: JOSÉ M. PORCEL AND Y.C. GARY LEE
- Issue published online: 30 MAR 2011
- Article first published online: 30 MAR 2011
- Accepted manuscript online: 1 MAR 2011 06:40AM EST
- Received 1 February 2011; invited to revise 13 February 2011; revised 21 February 2011; accepted 22 February 2011.
- atypical mesothelial cell hyperplasia;
- solitary fibrous tumour
Primary and metastatic pleural neoplasms, and non-neoplastic pleural diseases, can have similar clinical, radiographic and gross features. However, treatments and prognoses of these diverse pleural conditions vary greatly. Accurate diagnosis of pleural disease is therefore extremely important, and histological interpretation of pleural biopsies is vital to rendering an accurate diagnosis. Smaller biopsies contribute to the difficulties in accurately characterizing pleural lesions, and immunostains are frequently employed in their assessment. Diffuse malignant mesothelioma, the most common primary pulmonary neoplasm, is rare; however, other less common primary pleural neoplasms, including solitary fibrous tumour, the most common benign primary pleural neoplasm, occur. These neoplasms are discussed. Also, non-neoplastic pleural diseases, including granulomatous pleuritis, eosinophilic pleuritis and fibrous and fibrinous pleuritis, among other diseases, are discussed.