• 1
    Torres-Duque C, Maldonado D, Pérez-Padilla R et al. Biomass fuels and respiratory diseases. A review of the evidence. Proc. Am. Thorac. Soc. 2008; 5: 57790.
  • 2
    World Health Organization. Fuel for Life: Household Energy and Health. World Health Organization, Geneva, 2006.
  • 3
    Brown JR, Thornton JL. Percivall Pott (1714-1788) and chimney sweepers' cancer of the scrotum. Br. J. Ind. Med. 1957; 14: 6870.
  • 4
    International Agency for Research on Cancer (IARC). Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 95. Household Use of Solid Fuels and High-Temperature Frying. IARC, Lyon, 2010. [Downloaded 10 June 2011.] Available from URL:
  • 5
    World Health Organization and United Nations Development Programme. The Energy Access Situation in Developing Countries: A Review Focusing on Least Developed Countries and Sub-Saharan Africa. WHO Press, Geneva, 2009. [Accessed 10 June 2011.] Available from URL:
  • 6
    Barnes D, Krutilla K, Hyde W. The Urban Household Energy Transition: Energy, Poverty and the Environment in the Developing World. Resources for the Future Press, Washington DC, 2005.
  • 7
    McDonald JD, Zielinska B, Fujita EM et al. Fine particle and gaseous emission rates from residential wood combustion. Environ. Sci. Technol. 2000; 34: 208091.
  • 8
    Zhang J, Smite KR, Ma Y et al. Greenhouse gases and other airborne pollutants from household stoves in China: a database for emission factors. Atmos. Environ. 2000; 34: 453749.
  • 9
    Kleeman MJ, Schauer JJ, Cass GR. Size and composition distribution of fine particulate matter emitted from wood burning, meat charbroiling and cigarettes. Environ. Sci. Technol. 1999; 33: 351623.
  • 10
    Srogi K. Monitoring of environmental exposure to polycyclic aromatic hydrocarbons: a review. Environ. Chem. Lett. 2007; 5: 16995.
  • 11
    Wang D, Yang M, Jia H et al. Seasonal variation of polycyclic aromatic hydrocarbon in soil and air of Dalian areas, China: an assessment of soil-air exchange. J. Environ. Monit. 2008; 10: 107683.
  • 12
    World Health Organization Regional Office for Europe. WHO Guidelines for Indoor Air Pollution: Selected Pollutants. World Health Organization, Bonn, 2010. [Downloaded 10 June 2011.] Available from URL:
  • 13
    National Council on Radiation Protection and Measurements (NCRP). Deposition, Retention and Dosimetry of Inhaled Radioactive Substances (Report No. 125). NCRP, Bethesda, MD, 1997.
  • 14
    Oberdöster G. Lung clearance of inhaled insoluble and soluble particles. J. Aerosol Med. 1988; 1: 289330.
  • 15
    Morrow PE. Dust overloading of the lungs: update and appraisal. Toxicol. Appl. Pharmacol. 1992; 113: 112.
  • 16
    Warheit DB, Hansen JF, Yuen IS et al. Inhalation of high concentrations of low toxicity dusts in rats results in impaired pulmonary clearance mechanisms and persistent inflammation. Toxicol. Appl. Pharmacol. 1997; 145: 1022.
  • 17
    Muhle H, Bellmann B, Creutzenberg O et al. Pulmonary response to toner upon chronic inhalation exposure in rats. Fundam. Appl. Toxicol. 1991; 17: 28099.
  • 18
    International Agency for Research on Cancer (IARC). Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 92. Some Non-Heterocyclic Polycyclic Aromatic Hydrocarbons and Some Related Exposures. IARC, Lyon, 2010. [Downloaded 10 June 2011.] Available from URL:
  • 19
    Denissenko MF, Pao A, Tang M-S et al. Preferential formation of B(a)P adducts at lung cancer mutational hotspots in P53. Science 1996; 274: 4302.
  • 20
    Ross JA, Nesnow S. Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations. Mutat. Res. 1999; 424: 15566.
  • 21
    Gammon MD, Sagiv SK, Eng SM et al. Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis. Arch. Environ. Health 2004; 59: 6409.
  • 22
    Rybicki BA, Neslund-Dudas C, Bock CH et al. Polycyclic aromatic hydrocarbon-DNA adducts in prostate and biochemical recurrence after prostatectomy. Clin. Cancer Res. 2008; 14: 7507.
  • 23
    Peluso M, Munnia A, Hoek G et al. DNA adducts and lung cancer risk: a prospective study. Cancer Res. 2005; 65: 84028.
  • 24
    Flowers-Geary L, Harvey RG, Penning TM. Cytotoxicity of polycyclic aromatic hydrocarbon o-quinones in rat and human hepatoma cells. Chem. Res. Toxicol. 1993; 6: 25260.
  • 25
    Tannheimer SL, Ethier SP, Caldwell KK et al. Benzo(a)pyrene- and TCDD-induced alterations in tyrosine kinase phosphorylation and insulin-like growth factor signaling pathways in the MCF-10A human mammary epithelial cell line. Carcinogenesis 1999; 19: 12917.
  • 26
    Jiménez M, Aranda FJ, Teruel JA et al. The chemical toxic benzo(a)pyrene perturbs the physical organization of phosphatidylcholine membranes. Environ. Toxicol. Chem. 2002; 21: 78793.
  • 27
    Burdick AD, Davis JW 2nd, Liu KJ et al. Benzo(a)pyrene quinines increase cell proliferation, generate reactive oxygen species, and transactivate the epidermal growth factor receptor in breast epithelial cells. Cancer Res. 2003; 63: 782533.
  • 28
    Rudin CM, Avila-Tang E, Harris CC et al. Lung cancer in never smokers: Molecular profiles and therapeutic implications. Clin. Cancer Res. 2009; 15: 564661.
  • 29
    Hytönen S, Alfheim I, Sorsa M. Effect of emissions from residential wood stoves on SDCE induction in CHO cells. Mutat. Res. 1983; 118: 6975.
  • 30
    Salomaa S, Sorsa M, Alfheim I et al. Genotoxic effects of smoke emissions in mammalian cells. Environ. Int. 1985; 11: 3116.
  • 31
    Leonard SS, Wang S, Shi X et al. Wood smoke particles generate free radicals and cause lipid peroxidation, DNA damage, NFkappaB activation and TNF-alpha release in macrophages. Toxicology 2000; 150: 14757.
  • 32
    Karlsson HL, Ljungman AG, Lindbom J et al. Comparison of genotoxic amd inflammatory effects of particles generated by wood combustion, a road simulator and collected from street and subway. Toxicol. Lett. 2006; 165: 20311.
  • 33
    Alfheim I, Ramdahl T. Contribution of wood combustion to indoor air pollution as measured by mutagenicity in Salmonella and polycyclic aromatic hydrocarbon concentration. Environ. Mutagen. 1984; 6: 12130.
  • 34
    Bell DA, Kamens RM. Evaluation of the mutagenicity of combustion particles from several common biomass fuels in the Ames/Salmonella microsome test. Mutat. Res. 1990; 245: 17783.
  • 35
    Mumford JL, Helmes CT, Lee XM et al. Mouse skin tumorigenicity studies of indoor coal and wood combustion emissions from homes of residents in Xuan Wei, China with high lung cancer mortality. Carcinogenesis 1990; 11: 397403.
  • 36
    Liang CK, Quan N, Cao SR et al. Natural inhalation exposure to coal smoke and wood smoke induces lung cancers in mice and rats. Biomed. Environ. Sci. 1988; 1: 4250.
  • 37
    Mumford JL, Lee X, Lewtas J et al. DNA adducts as biomarkers for assessing exposure to polycyclic aromatic hydrocarbons in tissues from Xuan Wei women with high exposures to coal combustion emissions and high lung cancer mortality. Environ. Health Perspect. 1983; 99: 837.
  • 38
    Delgado J, Martinez LM, Sanchez TT et al. Lung cancer pathogenesis associated with wood smoke exposure. Chest 2005; 128: 12431.
  • 39
    Musthapa MS, Lohani M, Tiwari S et al. Cytogenetic biomonitoring of Indian women cooking with biofuels: micronucleus and chromosomal aberration test in peripheral blood lymphocytes. Environ. Mol. Mutagen. 2004; 43: 2439.
  • 40
    Kato M, Loomis D, Brooks LM et al. Urinary biomarkers in charcoal workers exposed to wood smoke in Bahia State, Brazil. Cancer Epidemiol. Biomarkers Prev. 2004; 13: 100512.
  • 41
    Venners SA, Wang B, Ni J et al. Indoor air pollution and respiratory health in urban and rural China. Int. J. Occup. Environ. Health 2000; 1: 17381.
  • 42
    Smith KR, Apte MG, Ma Y et al. Air pollution and the energy ladder in Asian cities. Energy 1994; 19: 587600.
  • 43
    Mumford JL, He XZ, Chapman RS et al. Lung cancer and indoor air pollution in Xuan Wei, China. Science 1987; 235: 21720.
  • 44
    Aggarwal AL, Raiyani CV, Patel PD et al. Assessment of exposure to benzo(a)pyrene in air for various population groups in Ahmedabad. Atmos. Environ. 1982; 16: 86770.
  • 45
    Chen CJ, Wu HY, Chuang YC et al. Epidemiologic characteristics and multiple risk factors of lung cancer in Taiwan. Anticancer Res. 1990; 10: 9716.
  • 46
    Shen XB, Wang GX, Huang YZ et al. Analysis and estimates of attributable risk factors for lung cancer in Nanjing, China. Lung Cancer 1996; 14: S10712.
  • 47
    Mzileni O, Sitas F, Steyn K et al. Lung cancer, tobacco and environmental factors in the African population of the Northern Province, South Africa. Tob. Control 1999; 8: 398401.
  • 48
    Pisani P, Srivatanakul P, Randerson-Moor J et al. GSTM1 and CYP1A1 polymorphisms, tobacco, air pollution, and lung cancer: a study in rural Thailand. Cancer Epidemiol. Biomarkers Prev. 2006; 15: 66774.
  • 49
    Ramanakumar AV, Parent ME, Siemiatycki J. Risk of lung cancer from residential heating and cooking fuels in Montreal, Canada. Am. J. Epidemiol. 2007; 165: 63442.
  • 50
    Behera D, Balamugesh T. Indoor air pollution as a risk factor for lung cancer in women. J. Assoc. Physicians India 2005; 53: 1902.
  • 51
    Xu Z-Y, Blot BJ, Xiao H-P et al. Smoking, air pollution, and the high rates of lung cancer in Shenyang, China. J. Natl Cancer Inst. 1989; 81: 18006.
  • 52
    Wu-Williams AH, Dai XD, Blot W et al. Lung cancer among women in north-east China. Br. J. Cancer 1990; 62: 9827.
  • 53
    Koo LC, Lee N, Ho JH. Do cooking fuels pose a risk for lung cancer? A case-control study of women in Hong Kong. Ecol. Dis. 1983; 2: 25565.
  • 54
    Liu Q, Sasco AJ, Riboli E et al. Indoor air pollution and lung cancer in Guangzhou, People's Republic of China. Am. J. Epidemiol. 1993; 137: 14554.
  • 55
    Gao Y-T, Blot WJ, Zheng W et al. Lung cancer among Chinese women. Int. J. Cancer 1987; 40: 6049.
  • 56
    Ko Y, Lee CH, Chen MJ et al. Risk factors for primary lung cancer among non-smoking women in Taiwan. Int. J. Epidemiol. 1997; 26: 2431.
  • 57
    Lee CH, Ko YC, Cheng LS et al. The heterogeneity in risk factors of lung cancer and the differences of histologic distribution between genders in Taiwan. Cancer Causes Control 2001; 12: 289300.
  • 58
    Sobue T. Association of indoor air pollution and lifestyle with lung cancer in Osaka, Japan. Int. J. Epidemiol. 1990; 19: S626.
  • 59
    Malats N, Camus-Radon AM, Nyberg F et al. Lung cancer risk in nonsmokers and GSTM1 and GSTT1 genetic polymorphism. Cancer Epidemiol. Biomarkers Prev. 2000; 9: 82733.
  • 60
    Gupta D, Baofetta P, Gaborieau V et al. Risk factors of lung cancer in Chandigarh, India. Indian J. Med. Res. 2001; 113: 14250.
  • 61
    Hernández-Garduño E, Brauer M, Pérez-Neria J et al. Wood smoke exposure and lung adenocarcinoma in non-smoking Mexican women. Int. J. Tuberc. Lung Dis. 2004; 8: 37783.
  • 62
    Lissowska J, Bardin-Mikolajczak A, Fletcher T et al. Lung cancer and indoor pollution from heating and cooking with solid fuels. Am. J. Epidemiol. 2005; 162: 32633.
  • 63
    Tang L, Lim W-Y Eng P et al. Lung cancer in Chinese women: evidence for an interaction between tobacco smoking and exposure to inhalants in the indoor environment. Environ. Health Perspect. 2010; 118: 125760.
  • 64
    Sapkota A, Gajalakshmi V, Jetly DH et al. Indoor air pollution from solid fuels and risk of hypopharyngeal/laryngeal and lung cancers: a multicentric case–control study from India. Int. J. Epidemiol. 2008; 37: 3218.
  • 65
    Hosgood HD III, Boffetta P, Greenland S et al. In-home coal and wood use and lung cancer risk: a pooled analysis of the International Lung Cancer Consortium. Environ. Health Perspect. 2010; 118: 17437.
  • 66
    Rothman KJ, Greenland S, Lash TL. Modern Epidemiology, 3rd edn. Lippincott, Williams and Wilkins, Philadelphia, PA, 2008.
  • 67
    Sidorchuk A, Agardh EE, Aremu O et al. Socioeconomic differences in lung cancer incidence: a systematic review and meta-analysis. Cancer Causes Control 2009; 20: 45971.
  • 68
    Lubin JH, Blot WJ. Assessment of lung cancer risk factors by histologic category. J. Natl Cancer Inst. 1984; 73: 3839.
  • 69
    Kajekar R. Environmental factors and developmental outcomes in the lung. Pharmacol. Ther. 2007; 114: 12945.
  • 70
    Smith GD, Ebrahim S. ‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease? Int. J. Epidemiol. 2003; 32: 122.
  • 71
    Lan Q, He X, Costa DJ et al. Indoor coal combustion emissions, GSTM1 and GSTT1 genotypes, and lung cancer risk: a case-control study in Xuan Wei, China. Cancer Epidemiol. Biomarkers Prev. 2000; 9: 6058.
  • 72
    Sinton JE, Smith KR, Peabody JW et al. An assessment of programs to promote improved household stoves in China. Energy for Sustainable Development 2004; 8: 3352.
  • 73
    Dutta K, Shields KN, Edwards R et al. Impact of improved biomass cookstoves on indoor air quality near Pune, India. Energy for Sustainable Development 2007; 11: 1932.