The Authors: S. Rodrigo Burguete, MD, is a Pulmonary and Critical Care Fellow with research interests in lung transplantation and critical care. Diego J. Maselli, MD, is a Pulmonary and Critical Care Fellow with research interests in obstructive lung disease, lung transplantation and pneumonia. Juan F. Fernandez, MD, is a Pulmonary and Critical Care Fellow with research interests in pneumonia, lung transplantation and critical care. Stephanie M. Levine, MD, is a Professor and Fellowship Program Director with research interests in lung transplantation, pulmonary issues in women and medical education.
INVITED REVIEW SERIES: TRANSLATING RESEARCH INTO PRACTICE†
Lung transplant infection
Version of Record online: 26 DEC 2012
© 2012 The Authors. Respirology © 2012 Asian Pacific Society of Respirology
Volume 18, Issue 1, pages 22–38, January 2013
How to Cite
BURGUETE, S. R., MASELLI, D. J., FERNANDEZ, J. F. and LEVINE, S. M. (2013), Lung transplant infection. Respirology, 18: 22–38. doi: 10.1111/j.1440-1843.2012.02196.x
SERIES EDITORS: JOHN E HEFFNER AND DAVID CL LAM
- Issue online: 26 DEC 2012
- Version of Record online: 26 DEC 2012
- Accepted manuscript online: 16 MAY 2012 07:47AM EST
- Received 1 February 2012; invited to revise 26 February 2012; revised 1 March 2012; accepted 8 March 2012.
- bacterial pneumonia;
- lung transplantation
Lung transplantation has become an accepted therapeutic procedure for the treatment of end-stage pulmonary parenchymal and vascular disease. Despite improved survival rates over the decades, lung transplant recipients have lower survival rates than other solid organ transplant recipients. The morbidity and mortality following lung transplantation is largely due to infection- and rejection-related complications. This article will review the common infections that develop in the lung transplant recipient, including the general risk factors for infection in this population, and the most frequent bacterial, viral, fungal and other less frequent opportunistic infections. The epidemiology, diagnosis, prophylaxis, treatment and outcomes for the different microbial pathogens will be reviewed. The effects of infection on lung transplant rejection will also be discussed.