Myopathy and neurogenic muscular atrophy in unexpected cardiopulmonary arrest
Article first published online: 29 JUL 2010
© 2011 The Authors.Pediatrics International © 2011 Japan Pediatric Society
Volume 53, Issue 2, pages 159–161, April 2011
How to Cite
Kawashima, H., Ishii, C., Yamanaka, G., Ioi, H., Nishimata, S., Kashiwagi, Y., Takekuma, K., Miyajima, T., Hoshika, A., Nishino, I. and Nonaka, I. (2011), Myopathy and neurogenic muscular atrophy in unexpected cardiopulmonary arrest. Pediatrics International, 53: 159–161. doi: 10.1111/j.1442-200X.2010.03211.x
- Issue published online: 19 APR 2011
- Article first published online: 29 JUL 2010
- Accepted manuscript online: 29 JUL 2010 12:00AM EST
- Received 14 January 2010; revised 30 April 2010; accepted 25 June 2010.
- cardiopulmonary arrest;
- congenital fiber type disproportion;
- nemaline myopathy;
- spinal muscular atrophy;
- sudden unexpected death
Background: Neuromuscular disorders can be the cause of sudden death of infants because of their weakness and gastroesophageal reflux (GER).
Methods: Muscle biopsy and genetic studies were performed by usual method.
Results: In this report four cases of infants with neuromuscular disorders (two cases of congenital myopathy and two cases of spinal muscular atrophy) who had unexpected cardiopulmonary arrest on arrival (CPAOA) are presented. Two of the cases did not show any symptoms, such as muscle weakness prior to CPAOA. The diagnosis was based on the results of the muscle biopsy and genetic examination.
Conclusion: These results suggest that sudden infant death caused by neuromuscular disorders should be considered.