• anxiety;
  • depression;
  • health-related quality of life;
  • lower urinary tract symptoms;
  • pain;
  • psychiatric morbidity

Background: This study aimed to evaluate the association of factors such as pain, lower urinary tract symptoms (LUTS), anxiety, depression and psychiatric morbidity on health-related quality of life (HRQoL) of patients with LUTS.

Methods: A total of 227 patients with LUTS were recruited into the study. The patients were assessed on pain, LUTS, anxiety, depression, psychiatric morbidity and health-related quality of life (HRQoL) using standardized questionnaires.

Results: The study showed that after adjustment, age, pain, anxiety, depression, psychiatric morbidity and LUTS contributed 31%, 13%, 45%, 16% and 48% respectively to the variability of the physical, mental, social, global and overall HRQoL.

Conclusion: Age, pain, psychiatric morbidity, anxiety and depression are associated with HRQoL among patients with LUTS.