Hyperbaric oxygen therapy for interstitial cystitis resistant to conventional treatments
Version of Record online: 21 JUN 2007
International Journal of Urology
Volume 14, Issue 6, pages 563–565, June 2007
How to Cite
Tanaka, T., Kawashima, H., Makino, T., Kamikawa, S., Kato, N. and Nakatani, T. (2007), Hyperbaric oxygen therapy for interstitial cystitis resistant to conventional treatments. International Journal of Urology, 14: 563–565. doi: 10.1111/j.1442-2042.2007.01599.x
- Issue online: 21 JUN 2007
- Version of Record online: 21 JUN 2007
- Received 27 February 2006; accepted 18 May 2006.
- Hunner's ulcer;
- hyperbaric oxygen;
- interstitial cystitis;
- visual analog scale
Abstract: We treated two cases of interstitial cystitis (IC) that were resistant to some conventional therapies with hyperbaric oxygen (HBO). Both patients underwent 20 sessions of 100% oxygen inhalation (2.0 atmosphere absolute for 60 min/day × 5 days/week for 4 weeks) in a hyperbaric chamber. The period of follow up was 12 months for case 1 and 9 months for case 2. After a course of HBO, the bladder mucosal ulcer (Hunner's ulcer) disappeared, and changes from baseline in pain and urinary frequency was constitutively inhibited. There were no adverse events during the 20 treatment sessions. One woman (case 1) had mild Eustachian tube dysfunction, resulting in a transient hearing impairment. HBO seems to be an option for treatment of IC resistant to conventional therapies.