Prevalence of genital mycoplasmas and ureaplasmas in men younger than 40 years-of-age with acute epididymitis
Article first published online: 5 DEC 2011
© 2011 The Japanese Urological Association
International Journal of Urology
Volume 19, Issue 3, pages 234–238, March 2012
How to Cite
Ito, S., Tsuchiya, T., Yasuda, M., Yokoi, S., Nakano, M. and Deguchi, T. (2012), Prevalence of genital mycoplasmas and ureaplasmas in men younger than 40 years-of-age with acute epididymitis. International Journal of Urology, 19: 234–238. doi: 10.1111/j.1442-2042.2011.02917.x
- Issue published online: 21 FEB 2012
- Article first published online: 5 DEC 2011
- Received 2 August 2011; accepted 30 October 2011.; Online publication 5 December 2011
- acute epididymitis;
- Mycoplasma genitalium;
- Mycoplasma hominis;
- Ureaplasma parvum;
- Ureaplasma urealyticum
Objectives: Acute epididymitis is often associated with urethritis. Mycoplasma genitalium and Ureaplasma urealyticum have been considered as pathogens of urethritis. The aim of the present study was to determine the prevalence of these microorganisms in men with acute epididymitis.
Method: A total of 56 men younger than 40 years-of-age with acute epididymitis were enrolled in the present study between January 2006 and June 2010. First-void urine specimens were subjected to culture of aerobic bacterial species, and examined for the presence of Chlamydia trachomatis, M. genitalium, M. hominis, U. parvum and U. urealyticum by polymerase chain reaction-based assays. Urethral swabs were cultured for Neisseria gonorrhoeae.
Results: The number and percentage of patients positive for each microorganism were as follows: Gram-negative bacilli, 2% and 3.6%; Gram-positive cocci, 23% and 41.1%; N. gonorrhoeae, 3% and 5.4%; C. trachomatis, 28% and 50.0%; M. genitalium, 5% and 8.9%; M. hominis, 6% and 10.7%; U. parvum, 6% and 10.7%; and U. urealyticum, 5% and 8.9%. Among 25 men with non-chlamydial non-gonococcal epididymitis, who were negative for Gram-negative bacilli, M. genitalium or U. urealyticum was detected in one man each (4.0%), and M. hominis and/or U. parvum was detected in five (20.0%).
Conclusion: In men younger than 40 years-of-age with acute epididymitis, C. trachomatis is a major pathogen. The prevalence of genital mycoplasmas and ureaplasmas are lower, and the role of genital mycoplasmas and ureaplasmas in the development of acute epididymitis remains to be determined.