Serum oxidant/antioxidant balance in exfoliation syndrome

Laboratory Science

  1. Ayça Yılmaz MD1,
  2. Ufuk Adıgüzel MD1,
  3. Lülüfer Tamer PhD2,
  4. Özlem Yıldırım MD1,
  5. Özay Öz MD1,
  6. Halil Vatansever MD1,
  7. Bahadır Ercan PhD2,
  8. Ula¸s Değirmenci MSC2,
  9. Uğur Atik MD2

Article first published online: 24 JAN 2005

DOI: 10.1111/j.1442-9071.2005.00944.x

Issue

Clinical & Experimental Ophthalmology

Clinical & Experimental Ophthalmology

Volume 33, Issue 1, pages 63–66, February 2005

Additional Information

How to Cite

Yılmaz, A., Adıgüzel, U., Tamer, L., Yıldırım, Ö., Öz, Ö., Vatansever, H., Ercan, B., Değirmenci, U. and Atik, U. (2005), Serum oxidant/antioxidant balance in exfoliation syndrome. Clinical & Experimental Ophthalmology, 33: 63–66. doi: 10.1111/j.1442-9071.2005.00944.x

Author Information

  1. 1

    Departments of Ophthalmology

  2. 2

    Biochemistry, Mersin University Faculty of Medicine, Mersin, Turkey

*Correspondence: Dr Ayça Yılmaz, Mersin Üniversitesi Tıp Fakültesi Hastanesi, Göz Hastalıkları AD, 33079, Mersin, Turkey. Email: aycayilmaz@mersin.edu.tr

Publication History

  1. Issue published online: 24 JAN 2005
  2. Article first published online: 24 JAN 2005

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Keywords:

  • antioxidants;
  • exfoliation syndrome;
  • malondialdehyde;
  • oxidants;
  • vitamin C

Abstract

Background: To evaluate the relationship between the serum oxidant–antioxidant balance and the presence of exfoliation syndrome (XFS) in a prospective study.

Methods: The study group comprised 27 cases of XFS. Serum concentrations of myeloperoxidase, malondialdehyde, vitamins A, C and E, catalase and total antioxidant were measured and compared with an independent group by t-test.

Results: Serum myeloperoxidase, vitamins A and E, catalase and total antioxidant parameters were not statistically different among the groups (P > 0.05). Serum vitamin C concentrations were significantly lower and malondialdehyde concentrations were significantly higher in cases of XFS when compared with the control group (P = 0.008 and P = 0.002, respectively).

Conclusion: An altered oxidant–antioxidant balance may play a role in the pathogenesis of XFS.

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