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Marked discordance for myopia in female monozygotic twins

Authors

  • Mohamed Dirani BOrth & OphthSc(Hons),

    1. Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, and
    2. Vision Cooperative Research Centre, Sydney, New South Wales, Australia
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  • Matthew Chamberlain MBBS,

    1. Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, and
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  • Pam Garoufalis BOrth(Hons),

    1. Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, and
    2. Vision Cooperative Research Centre, Sydney, New South Wales, Australia
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  • Christine Chen MBBS,

    1. Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, and
    2. Vision Cooperative Research Centre, Sydney, New South Wales, Australia
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  • Robyn H Guymer FRANZCO PhD,

    1. Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, and
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  • Paul N Baird PhD

    1. Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, and
    2. Vision Cooperative Research Centre, Sydney, New South Wales, Australia
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Abstract

Female monozygotic twins aged 54 years discordant for myopia are reported. One twin presented with bilateral high myopia (right eye = −6.00/+0.50 × 5°, left eye = −6.00/+0.50 × 45°) and her identical twin had no significant refractive error (right eye = −0.50/plano, left eye = −0.50/+0.75 × 40°). An explanation for the striking refractive discordance seen in this case report is yet to be determined.

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