Sticky platelet syndrome and anterior ischaemic optic neuropathy
Article first published online: 8 NOV 2007
Clinical & Experimental Ophthalmology
Volume 35, Issue 8, pages 779–781, November 2007
How to Cite
Randhawa, S. and Van Stavern, G. P. (2007), Sticky platelet syndrome and anterior ischaemic optic neuropathy. Clinical & Experimental Ophthalmology, 35: 779–781. doi: 10.1111/j.1442-9071.2007.01583.x
- Issue published online: 8 NOV 2007
- Article first published online: 8 NOV 2007
- Received 20 December 2006; accepted 21 June 2007.
- optic disc oedema;
- optic neuropathy;
We report a young patient who presented with nonarteritic anterior ischaemic optic neuropathy associated with the sticky platelet syndrome (SPS, a congenital prothrombotic disorder). A 15-year-old boy presented with a sudden, painless onset of a right inferior altitudinal visual field defect and marked optic disc oedema. Cranial magnetic resonance imaging (including orbits), orbital ultrasound and haematological investigations including a routine hypercoagulability work-up were negative. Further evaluation showed a positive assay for SPS which was confirmed on repeat testing. The SPS (characterized by platelet hyperaggregability and vascular occlusion) may be a potential thrombophilic risk factor for nonarteritic anterior ischaemic optic neuropathy.