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To investigate the prevalence of polypoidal choroidal vasculopathy in presumed age-related peripapillary subretinal neovascular membranes
Article first published online: 6 APR 2009
DOI: 10.1111/j.1442-9071.2009.02044.x
© 2009 The Authors. Journal compilation © 2009 Royal Australian and New Zealand College of Ophthalmologists
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How to Cite
Squirrell, D. M., Bacon, J. F. and Brand, C. S. (2009), To investigate the prevalence of polypoidal choroidal vasculopathy in presumed age-related peripapillary subretinal neovascular membranes. Clinical & Experimental Ophthalmology, 37: 368–372. doi: 10.1111/j.1442-9071.2009.02044.x
Publication History
- Issue published online: 30 JUN 2009
- Article first published online: 6 APR 2009
- Received 22 December 2008; accepted 12 March 2009.
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Keywords:
- peripapillary subretinal neovascular membrane;
- polypoidal choroidal vasculopathy
Abstract
Background: To investigate the prevalence and angiographic appearances of polypoidal choroidal vasculopathy (PCV) masquerading as age-related peripapillary subretinal neovascular membranes (PSRNVM).
Methods: A consecutive case series of all patients investigated for presumed age-related PSRNVM in our tertiary referral centre over the period September 2006–2007. The presenting clinical features and fundus fluorescein angiographic (FFA) characteristics of each patient's lesion were identified. Any accompanying Indocyanine Green Angiogram (ICGA) was also reviewed, and on the basis of this investigation patients were classified into one of three groups: proven PCV, probable PCV and PSRNVM.
Results: Thirty patients with presumed age-related PSRNVM were identified. The FFA leakage pattern was occult in 21 patients and classic in nine patients. Sixteen patients also had ICGA performed. In 14 of these patients the original FFA leakage pattern was occult, and in two it was classic. Of the 14 patients with occult leakage on FFA who subsequently underwent ICGA all were found to have PCV.
Conclusions: PCV is important and underrecognized in presumed age-related PSRNVMs. In such cases, particularly when the pattern of leakage on the fluorescein angiogram is occult, ICGA should be performed to identify the site of the polyps and if required to direct treatment.