Clinical study of Acrysof IQ aspheric intraocular lenses


  • Financial support: Shanghai Leading Academic Discipline Project (S30205).

Dr Min Luo, Shanghai 9th Hospital Ophthalmology Department, Shanghai Jiaotong University, No 639 ZhiZao Ju Road, Shanghai 200011, China. Email:


Purpose:  To determine whether implantation of an aspheric intraocular lens (SN 60 WF Alcon) results in reduced spherical aberration and improved contrast sensitivity after cataract surgery.

Methods:  Randomized, prospective study. 260 patients/eyes were randomized to receive two intraocular lens types: Alcon Acrysof Natural (136 eyes) and Acrysof IQ (124 eyes). Quality of vision was measured by visual acuity and contrast sensitivity under mesopic and photopic conditions. Ocular aberrations for 4.0- and 6.0-mm pupil were measured with Allegretto Wavelight Analyzer. All ophthalmologic were performed 7, 30 and 90 days postoperatively. Visual function index (VF-14) questionnaires for cataract symptoms were performed 90 days after surgery by all the patients.

Results:  After 90 days, all eyes had mean postoperative best spectacle-corrected visual acuity 0.75. Eyes with the Acrysof IQ had significantly higher contrast sensitivity than eyes with the Acrysof Natural at high and middle spatial frequencies. A significant reduction in spherical aberration after Acrysof IQ implantation was achieved. The Acrysof IQ also had lower values of high-order aberration with 4.0- and 6.0-mm pupil when compared with the AcrySof Natural.

Conclusion:  Results show the aspheric Acrysof IQ induced significantly less high-order aberration and spherical aberration compared with the Acrysof Natural. Contrast sensitivity revealed better values with the Acrysof IQ intraocular lens.