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Keywords:

  • Heidelberg Retina Tomograph;
  • optic nerve head;
  • optical coherence tomography

Abstract

Background:  To assess the agreement between the Heidelberg Retina Tomograph and Cirrus spectral-domain optical coherence tomography (Cirrus HD-OCT [Carl Zeiss Meditec, Dublin, CA, USA]) when measuring optic disc parameters.

Design:  Prospective, cross-sectional study.

Participants:  A total of 96 glaucoma patients and 21 normal subjects were analysed.

Methods:  Optic nerve head measurements, including disc area, rim area, cup-to-disc ratio and cup volume were obtained using both the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 (Heidelberg Engineering GmbH, Heidelberg, Germany).

Main Outcome Measurements:  Bland–Altman plots were used to evaluate the agreement between each of the optic disc parameters.

Results:  Although Cirrus HD-OCT values were smaller than Heidelberg Retina Tomograph 3 values for the disc and rim areas, overall the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 measurements were highly correlated (r = 0.657 to 0.821). As compared with Heidelberg Retina Tomograph 3, disc and rim areas tended to be minimized by Cirrus HD-OCT, especially when there were large disc and rim areas, although there was no relationship between the discrepancy and the level of measurement of the cup-to-disc ratio. The optical coherence tomography overestimated the Heidelberg Retina Tomograph-determined cup volume, especially when there were large cup volumes.

Conclusions:  Bland–Altman analyses revealed that with the exception of the cup-to-disc ratio, there was poor agreement between the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 morphometric measurements. In addition, with the exception of the cup-to-disc ratio, the optic nerve head measurements could not be directly compared between the Cirrus HD-OCT and Heidelberg Retina Tomograph 3.