Competing/conflicts of interest: No stated conflict of interest.
Comparison of optic nerve head parameters using Heidelberg Retina Tomograph 3 and spectral-domain optical coherence tomography
Article first published online: 17 MAY 2012
© 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists
Clinical & Experimental Ophthalmology
Volume 40, Issue 7, pages 721–726, September/October 2012
How to Cite
Sato, S., Hirooka, K., Baba, T. and Shiraga, F. (2012), Comparison of optic nerve head parameters using Heidelberg Retina Tomograph 3 and spectral-domain optical coherence tomography. Clinical & Experimental Ophthalmology, 40: 721–726. doi: 10.1111/j.1442-9071.2012.02782.x
Funding sources: No stated funding sources.
- Issue published online: 9 OCT 2012
- Article first published online: 17 MAY 2012
- Accepted manuscript online: 7 MAR 2012 07:21AM EST
- Received 19 October 2011; accepted 22 January 2012.
- Heidelberg Retina Tomograph;
- optic nerve head;
- optical coherence tomography
Background: To assess the agreement between the Heidelberg Retina Tomograph and Cirrus spectral-domain optical coherence tomography (Cirrus HD-OCT [Carl Zeiss Meditec, Dublin, CA, USA]) when measuring optic disc parameters.
Design: Prospective, cross-sectional study.
Participants: A total of 96 glaucoma patients and 21 normal subjects were analysed.
Methods: Optic nerve head measurements, including disc area, rim area, cup-to-disc ratio and cup volume were obtained using both the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 (Heidelberg Engineering GmbH, Heidelberg, Germany).
Main Outcome Measurements: Bland–Altman plots were used to evaluate the agreement between each of the optic disc parameters.
Results: Although Cirrus HD-OCT values were smaller than Heidelberg Retina Tomograph 3 values for the disc and rim areas, overall the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 measurements were highly correlated (r = 0.657 to 0.821). As compared with Heidelberg Retina Tomograph 3, disc and rim areas tended to be minimized by Cirrus HD-OCT, especially when there were large disc and rim areas, although there was no relationship between the discrepancy and the level of measurement of the cup-to-disc ratio. The optical coherence tomography overestimated the Heidelberg Retina Tomograph-determined cup volume, especially when there were large cup volumes.
Conclusions: Bland–Altman analyses revealed that with the exception of the cup-to-disc ratio, there was poor agreement between the Cirrus HD-OCT and Heidelberg Retina Tomograph 3 morphometric measurements. In addition, with the exception of the cup-to-disc ratio, the optic nerve head measurements could not be directly compared between the Cirrus HD-OCT and Heidelberg Retina Tomograph 3.