A. Ersay MD; G. Yilmaz MD; Y. Akgun; Y. Celik PhD.
FACTORS AFFECTING MORTALITY OF FOURNIER’S GANGRENE: REVIEW OF 70 PATIENTS
Article first published online: 30 JAN 2007
ANZ Journal of Surgery
Volume 77, Issue 1-2, pages 43–48, January/February 2007
How to Cite
Ersay, A., Yilmaz, G., Akgun, Y. and Celik, Y. (2007), FACTORS AFFECTING MORTALITY OF FOURNIER’S GANGRENE: REVIEW OF 70 PATIENTS. ANZ Journal of Surgery, 77: 43–48. doi: 10.1111/j.1445-2197.2006.03975.x
- Issue published online: 30 JAN 2007
- Article first published online: 30 JAN 2007
- Accepted for publication 25 June 2006.
- Fournier’s gangrene;
- Fournier’s Severity Index;
Background: Fournier’s disease is a potentially fatal, acute, gangrenous infection of the scrotum, penis or perineum associated with a synergistic bacterial infection of the subcutaneous fat and superficial fascia.
Methods: The clinical records of 70 patients treated for Fournier’s gangrene were evaluated retrospectively to determine prognostic indices and to stress Fournier’s Severity Index (FSI), influencing outcome.
Results: The mortality rate in this study was 22.8%. Length of the hospitalization time and FSI were detected as effective factors on mortality of Fournier’s gangrene (P < 0.05) by Binary Logistic Regression analysis and the area under the receiver operating characteristic curve of these variables was also found to be significant (P < 0.001). The average FSI was determined as 4.66 ± 2.31 in survivors and 11.56 ± 2.68 in non-survivors and 5.11 ± 2.83 in patients with primary genito-urinary infection but 7.56 ± 4.35 in primary anorectal infection. The FSI was also found predictive of hospitalization time and number of debridements among survivors.
Conclusion: Fournier’s Severity Index is a simplified way of comparing patients with this disease and may also have some significance in predicting outcome. The FSI is a more significant and predictive tool that should be popularized to predict the prognosis in Fournier’s gangrene.