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Prosthetic joint infection: challenges of diagnosis and treatment

  1. Trisha N. Peel1,*,
  2. Kirsty L. Buising2,
  3. Peter F. M. Choong1,3

Article first published online: 10 NOV 2010

DOI: 10.1111/j.1445-2197.2010.05541.x

Issue

ANZ Journal of Surgery

ANZ Journal of Surgery

Volume 81, Issue 1-2, pages 32–39, January/February 2011

Additional Information

How to Cite

Peel, T. N., Buising, K. L. and Choong, P. F. M. (2011), Prosthetic joint infection: challenges of diagnosis and treatment. ANZ Journal of Surgery, 81: 32–39. doi: 10.1111/j.1445-2197.2010.05541.x

Author Information

  1. 1

    Department of Surgery, University of Melbourne, St Vincent's Hospital Melbourne

  2. 2

    Department of Infectious Diseases, St Vincent's Hospital Melbourne

  3. 3

    Department of Orthopaedics, St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia

*Dr Trisha N. Peel, Department of Surgery, University of Melbourne, St Vincent's Hospital Melbourne, Fitzroy, Vic. 3065, Australia. Email: t.peel@pgrad.unimelb.edu.au

Publication History

  1. Issue published online: 7 FEB 2011
  2. Article first published online: 10 NOV 2010
  3. Accepted for publication 26 April 2010.

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Keywords:

  • arthroplasty infection;
  • bone and joint infection;
  • infectious disease;
  • orthopaedic surgery

Abstract

Arthroplasty for arthritis has led to remarkable improvement in patient quality of life and alleviation of symptoms. A major complication of this surgery is infection. This review examines current understanding of epidemiology, diagnosis, treatment and prevention of prosthetic joint infections. In particular, this article focuses on the role of biofilm formation in the pathogenesis of device infections and the diagnostic and treatment challenges associated with this process.

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