C.-C. Lin MD; P.-Y. Lin PhD; C.-J. Ko MD; Y.-L. Chen MD; S.-T. Chen, MD; S.-J. Kuo MD.
Hepatic resection for bilateral hepatolithiasis: a 20-year experience
Article first published online: 26 SEP 2012
© 2012 The Authors. ANZ Journal of Surgery © 2012 Royal Australasian College of Surgeons
ANZ Journal of Surgery
Volume 83, Issue 12, pages 978–984, December 2013
How to Cite
Lin, C.-C., Lin, P.-Y., Ko, C.-J., Chen, Y.-L., Chen, S.-T. and Kuo, S.-J. (2013), Hepatic resection for bilateral hepatolithiasis: a 20-year experience. ANZ Journal of Surgery, 83: 978–984. doi: 10.1111/j.1445-2197.2012.06283.x
- Issue published online: 2 DEC 2013
- Article first published online: 26 SEP 2012
- Manuscript Accepted: 19 AUG 2012
- bilateral hepatolithiasis;
- hepatic resection
There is increasing evidence showing that hepatic resection is probably the best definitive treatment for unilateral hepatolithiasis. However, the role of hepatic resection for bilateral hepatolithiasis is rarely mentioned in the literature.
We retrospectively reviewed 197 patients who underwent hepatic resection for hepatolithiasis in Changhua Christian Hospital from December 1987 to December 2007. A total of 156 patients with unilateral hepatolithiasis were defined as the UNI group (control group), and 41 patients with bilateral hepatolithiasis were defined as the BI group (study group). The short- and long-term outcomes were measured.
The BI group had longer operating time (200 min versus 173 min, P = 0.006), lower immediate stone clearance rate (56.1% versus 91.7%, P < 0.001), lower final stone clearance rate (75.6% versus 94.9%, P = 0.001), higher rate of stone recurrence (22.6% versus 6.1%, P = 0.009) and higher disease-related mortality (19.5% versus 5.1%, P = 0.006). Thirty patients with bilateral peripheral stones were indicated for bilateral hepatectomy, but only 20 (66.7%) of them actually underwent the proposed procedure. Of the patients who did not achieve immediate stone clearance, bilateral peripheral stones represented 88.9% (P = 0.044). Of the patients who had stone recurrence, patients less than 35 years old represented 42.9% (P = 0.007).
Bilateral hepatolithiasis has worse outcomes than unilateral hepatolithiasis after being treated with hepatic resection. Regarding bilateral peripheral stones, there is often a discrepancy between the extent of stone-affected parenchyma and that of final liver resection, resulting in a lower immediate stone clearance rate. A higher stone recurrence rate was observed among younger population.