*Department of Pathology, Princess Alexandra Hospital, Woolloongabba, Qld.
Mortality associated with ischaemic hepatitis
Article first published online: 25 MAR 2008
Australian and New Zealand Journal of Medicine
Volume 20, Issue 1, pages 32–34, February 1990
How to Cite
Hickman, P. E. and Potter, J. M. (1990), Mortality associated with ischaemic hepatitis. Australian and New Zealand Journal of Medicine, 20: 32–34. doi: 10.1111/j.1445-5994.1990.tb00366.x
- Issue published online: 25 MAR 2008
- Article first published online: 25 MAR 2008
- Accepted for publication: 8 June 1989
- Cited By
- Ischaemic hepatitis;
- aspartate aminotransferase circulatory failure;
- left ventricular failure
Twenty-nine patients of 18,000 inpatient admissions over a six-month period developed ischaemic hepatitis accompanied by peak aspartate aminotransferase (AST-EC 18.104.22.168) activity greater than 1,000 U/L. Seventeen of these 29 patients died either during or shortly after the episode of ischaemic hepatitis, with an overall mortality of 58.6%. Mortality was not due in any of the cases to the hepatitis but rather the underlying cause. Ischaemic hepatitis was the commonest cause of an AST activity greater than 1,000 U/L in this hospital population (29 of 52 patients i.e. 56%). This condition is more common than generally appreciated and is associated with a poor prognosis.