A fire inside: current concepts in chronic pancreatitis
Article first published online: 15 JUL 2008
© 2008 The Authors Journal compilation © 2008 Royal Australasian College of Physicians
Internal Medicine Journal
Volume 38, Issue 7, pages 592–598, July 2008
How to Cite
Tattersall, S. J. N., Apte, M. V. and Wilson, J. S. (2008), A fire inside: current concepts in chronic pancreatitis. Internal Medicine Journal, 38: 592–598. doi: 10.1111/j.1445-5994.2008.01715.x
Potential conflicts of interest: None
- Issue published online: 15 JUL 2008
- Article first published online: 15 JUL 2008
- Received 17 December 2007; accepted 18 April 2008.
- chronic pancreatitis;
- pancreatic stellate cell;
Chronic pancreatitis is a necroinflammatory process characterized pathologically by acinar atrophy and fibrosis and clinically by abdominal pain, diabetes and maldigestion. In this review we summarize some of the recent advances in the understanding of the pathogenesis of pancreatitis and how they have shaped our current understanding of chronic pancreatitis. We pay particular attention to advances in the genetic basis of idiopathic, hereditary and tropical pancreatitis as well as research into the relationship between alcohol and the pancreas. We have also reviewed current practices with respect to diagnosis and management of chronic pancreatitis.