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Diagnostic value of 18F-FDG PET/CT in patients with fever of unknown origin

Authors

  • Y. J. Kim,

    1. Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea
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  • S. I. Kim,

    Corresponding author
    1. Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea
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  • K-W. Hong,

    1. Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea
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  • M. W. Kang

    1. Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Korea
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  • Funding: None.

  • Conflict of interest: None.

Sang Il Kim, Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary's Hospital, The Catholic University of Korea, 505 Banpodong, Seochogu 137-701, Korea. Email: drksi@catholic.ac.kr

Abstract

This study investigates the diagnostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) in patients with 109 classical fever of unknown origin (FUO). Of the 48 18F-FDG PET/CT scans, 41 (85.4%) were interpreted as abnormal, and 25 (52.1% of all scans) were considered clinically helpful. The final cause of fever was determined in 41 patients (85.4%); infection (25%), malignancy (12.5%), non-infectious inflammatory disease (16.7%) and miscellaneous causes (31.3%). 18F-FDG PET/CT contributed to the final diagnosis of FUO in 65.8%.

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