Aromatase inhibitors in the treatment of recurrent ovarian granulosa cell tumors: Brief report and review of the literature
Article first published online: 5 DEC 2011
© 2011 The Authors. Journal of Obstetrics and Gynaecology Research © 2011 Japan Society of Obstetrics and Gynecology
Journal of Obstetrics and Gynaecology Research
Volume 38, Issue 1, pages 340–344, January 2012
How to Cite
AlHilli, M. M., Long, H. J., Podratz, K. C. and Bakkum-Gamez, J. N. (2012), Aromatase inhibitors in the treatment of recurrent ovarian granulosa cell tumors: Brief report and review of the literature. Journal of Obstetrics and Gynaecology Research, 38: 340–344. doi: 10.1111/j.1447-0756.2011.01698.x
- Issue published online: 4 JAN 2012
- Article first published online: 5 DEC 2011
- Received: January 19 2011.; Accepted: April 27 2011.
- aromatase inhibitor;
- ovarian granulosa cell tumor;
- ovarian sex chord stromal tumor
Granulosa cell tumors are ovarian sex cord stromal cancers that are unique for their indolent nature and late recurrence. Standard treatment regimens utilized include surgery, chemotherapy, and radiotherapy. However, hormonal suppression with aromatase inhibitors, which have shown promising results, may be a viable alternative to these modalities. We present a heavily pre-treated, multi-operated patient who experienced significant tumor shrinkage following treatment with an aromatase inhibitor for her recurrent granulosa cell tumor.