Fumarate hydratase gene mutation in two young patients with sporadic uterine fibroids
Article first published online: 6 JUL 2012
© 2012 The Authors. Journal of Obstetrics and Gynaecology Research © 2012 Japan Society of Obstetrics and Gynecology
Journal of Obstetrics and Gynaecology Research
Volume 39, Issue 1, pages 410–414, January 2013
How to Cite
Kubinova, K., Tesarova, M., Hansikova, H., Vesela, K., Kuzel, D. and Mara, M. (2013), Fumarate hydratase gene mutation in two young patients with sporadic uterine fibroids. Journal of Obstetrics and Gynaecology Research, 39: 410–414. doi: 10.1111/j.1447-0756.2012.01939.x
- Issue published online: 7 JAN 2013
- Article first published online: 6 JUL 2012
- Received: June 15 2011.; Accepted: April 14 2012.
Figure S1 Results of fumarate hydratase (FH) gene sequencing in DNA isolated from leucocytes of patient 1, patient 2, and control. The red arrow indicates position of the mutation.
Figure S2 Polymerase chain reaction (PCR)–restriction fragment length polymorphism (RFLP) testing for presence of c.584T>C mutation in FH gene in patient 2 leucocytes and uterine fibroid. DNA fragments of 249 bp and 150 bp correspond to wild-type allele. M, molecular size marker.
Table S1 Activities of fumarate hydratase and control enzyme citrate synthase in isolated blood lymphocytes.
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