The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK
Version of Record online: 28 APR 2005
European Journal of Neuroscience
Volume 21, Issue 8, pages 2051–2062, April 2005
How to Cite
Chierzi, S., Ratto, G. M., Verma, P. and Fawcett, J. W. (2005), The ability of axons to regenerate their growth cones depends on axonal type and age, and is regulated by calcium, cAMP and ERK. European Journal of Neuroscience, 21: 2051–2062. doi: 10.1111/j.1460-9568.2005.04066.x
- Issue online: 28 APR 2005
- Version of Record online: 28 APR 2005
- Received 15 September 2004, revised 27 December 2004, accepted 10 February 2005
Fig. S1. ERK inhibition does not affect growth cone motility of adult DRG growth cones. Time-lapse frames of DRG growth cones before and after administration of U0126. The inhibitor (20 ?M) was added to the medium 10 min after the start of the recording. Calibration bar is 5 ?m.
Fig. S2. The cAMP-increasing drugs forskolin (20 ?M) and IBMX (4 ?M) do not increase the motility of adult RGC growth cones. The drugs were added 30 min after the start of the recording. Calibration bar is 10 ?m.
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