Electrical coupling induces bistability of rhythms in networks of inhibitory spiking neurons

Authors

  • Tiaza Bem,

    1. Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Science, Warsaw, Poland
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    • *

      T.B. and Y.L.F. contributed equally to this study.

  • Yves Le Feuvre,

    1. Laboratoire de Neurobiologie des Réseaux, UMR 5816 Université Bordeaux I CNRS, 33405 Talence CEDEX, France
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    • *

      T.B. and Y.L.F. contributed equally to this study.

  • John Rinzel,

    1. Center for Neural Science and Courant Institute for Mathematical Sciences, New York University, 4 Washington Place, Rm 809, NY 10003, USA
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  • Pierre Meyrand

    1. Laboratoire de Neurobiologie des Réseaux, UMR 5816 Université Bordeaux I CNRS, 33405 Talence CEDEX, France
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Dr Pierre Meyrand, as above.
E-mail: p.meyrand@lnr.u-bordeaux1.fr

Abstract

Information processing in higher brain structures is thought to rely on the synchronization of spiking neurons. Increasing evidence indicates that, within these structures, inhibitory neurons are linked by both chemical and electrical synapses. However, how synchronized states may emerge from such circuits is not fully understood. Using snail neurons interconnected through a dynamic-clamp system, we show that networks of spiking neurons linked by both reciprocal inhibition and electrical coupling can express two coexisting coordination patterns of different rhythms. One of these patterns consists of antiphase firing of the network partners whereas, in the other, neurons fire synchronously. Switching between patterns may be evoked immediately by transient stimuli, demonstrating bistability of the network. Thus electrical coupling can provide a potent way for instantaneous reconfiguration of activity patterns in inhibitory spiking networks without alteration of intrinsic network properties by modulatory processes.

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