These authors contributed equally to this work.
Reciprocal connections between olfactory structures and the cortex of the rostral superior temporal sulcus in the Macaca fascicularis monkey
Article first published online: 18 NOV 2005
European Journal of Neuroscience
Volume 22, Issue 10, pages 2503–2518, November 2005
How to Cite
Mohedano-Moriano, A., Martinez-Marcos, A., Muñoz, M., Arroyo-Jimenez, M. M., Marcos, P., Artacho-Pérula, E., Blaizot, X. and Insausti, R. (2005), Reciprocal connections between olfactory structures and the cortex of the rostral superior temporal sulcus in the Macaca fascicularis monkey. European Journal of Neuroscience, 22: 2503–2518. doi: 10.1111/j.1460-9568.2005.04443.x
- Issue published online: 23 NOV 2005
- Article first published online: 18 NOV 2005
- Received 6 May 2005, revised 29 July 2005, accepted 12 September 2005
- association cortex;
- nonhuman primate;
- olfactory cortex;
- rostral temporal lobe
Convergence of sensory modalities in the nonhuman primate cerebral cortex is still poorly understood. We present an anatomical tracing study in which polysensory association cortex located at the fundus and upper bank of the rostral superior temporal sulcus presents reciprocal connections with primary olfactory structures. At the same time, projections from this polysensory area reach multiple primary olfactory centres. Retrograde (Fast Blue) and anterograde (biotinylated dextran–amine and 3H-amino acids) tracers were injected into primary olfactory structures and rostral superior temporal sulcus. Retrograde tracers restricted to the anterior olfactory nucleus resulted in labelled neurons in the rostral portion of the upper bank and fundus of superior temporal sulcus. Injections of biotinylated dextran–amine at the fundus and upper bank of the superior temporal sulcus confirmed this projection by labelling axons in the dorsal and lateral portions of the anterior olfactory nucleus, as well as piriform, periamygdaloid and entorhinal cortices. Retrograde tracer injections at the rostral superior temporal sulcus resulted in neuronal labelling in the anterior olfactory nucleus, piriform, periamygdaloid and entorhinal cortices, thus providing confirmation of the reciprocity between primary olfactory structures and the cortex at the rostral superior temporal sulcus. The reciprocal connections between the rostral part of superior temporal sulcus and primary olfactory structures represent a convergence for olfactory and other sensory modalities at the cortex of the rostral temporal lobe.