Task-related differential dynamics of EEG alpha- and beta-band synchronization in cortico-basal motor structures
Article first published online: 5 APR 2007
European Journal of Neuroscience
Volume 25, Issue 5, pages 1604–1615, March 2007
How to Cite
Klostermann, F., Nikulin, V. V., Kühn, A. A., Marzinzik, F., Wahl, M., Pogosyan, A., Kupsch, A., Schneider, G.-H., Brown, P. and Curio, G. (2007), Task-related differential dynamics of EEG alpha- and beta-band synchronization in cortico-basal motor structures. European Journal of Neuroscience, 25: 1604–1615. doi: 10.1111/j.1460-9568.2007.05417.x
- Issue published online: 5 APR 2007
- Article first published online: 5 APR 2007
- Received 11 August 2006, revised 16 January 2007, accepted 17 January 2007
- motor processing;
Movement-related processing results in the modulation of neuronal synchronization over several electroencephalography (EEG) frequency ranges, including alpha- (8–12 Hz) and beta-band (14–30 Hz). Whether modulation patterns differ across sites within the motor system remains unclear, but could denote how information is conveyed across the cortico-basal network. We therefore compared the event-related synchronization/desynchronization (ERS/ERD) in recordings from the scalp, basal ganglia and thalamic structures during a motor task.
Simultaneous depth and scalp EEG were recorded in 13 patients, undergoing deep brain stimulation of the thalamic ventral intermediate nucleus (VIM) or the subthalamic nucleus (STN). They performed a choice-reaction task with pre-cued Go-signals, instructive for either left- or right-sided button presses.
In the beta-band, pre-cues and Go-signals were followed by ERD starting well before and peaking at task execution, uniformly in all cortical and subcortical recordings. In contrast, a comparable alpha-band ERD was only seen at the scalp, whereas mirror-like ERS were observed in the motor-inhibitory STN. In VIM, which receives strong somatosensory afferences, a major alpha-ERD upon the Go-signal did not start until the motor response.
These dissociations of task-related Alpha- and Beta-band dynamics tag a functional diversity in cortico-basal networks, which are simultaneously active in motor processing. Whereas the uniform downregulation of Beta-activity points to an anti-kinetic operation mode throughout the motor system, site-dependent courses of Alpha-synchronization rather reflect the coordination of activity levels in functionally divergent motor structures during the preparation and execution of movements.