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Fig. S1. Expression patterns of GMR-Gal4 driver visualized with UAS-GFP-CAAX reporter during development. Fig. S2. Systemic distribution of TTR induced by increased expression of secreted TTR. Fig. S3. Age-dependent degenerative changes in TTR transgenic flies. Fig. S4. Detection of Thioflavine S-positive TTR deposits in 30-dayold flies. Fig. S5. Correlation of the dragged wing phenotype with reduced climbing performance. Fig. S6. Time course of wing phenotype development at different temperatures.

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