G.D., M.B. and O.W. contributed equally to this work.
M-type channels selectively control bursting in rat dopaminergic neurons
Article first published online: 17 FEB 2010
© The Authors (2010). Journal Compilation © Federation of European Neuroscience Societies and Blackwell Publishing Ltd
European Journal of Neuroscience
Volume 31, Issue 5, pages 827–835, March 2010
How to Cite
Drion, G., Bonjean, M., Waroux, O., Scuvée-Moreau, J., Liégeois, J.-F., Sejnowski, T. J., Sepulchre, R. and Seutin, V. (2010), M-type channels selectively control bursting in rat dopaminergic neurons. European Journal of Neuroscience, 31: 827–835. doi: 10.1111/j.1460-9568.2010.07107.x
- Issue published online: 1 MAR 2010
- Article first published online: 17 FEB 2010
- Received 9 September 2009, accepted 16 December 2009
Fig. S1. Effect of the i.p. administration of XE991 (3mg/kg) on the firing rate of DA neurons in the absence of a GABA antagonist.
Fig. S2. Comparison of the interspike intervals.
Fig. S3. Relative frequency of bursts as a function of their number of spikes, and changes in spike amplitude within bursts.
Fig. S4. Comparing i.p and iontophoretic application of vehicle
Fig. S5. Effect of M-channel blockade on the distribution of short interspike intervals.
Fig. S6. Effect of M-current blockade on a DA neuron model when the M current conductance was identical to the one reported experimentally.
Table S1: SR95531 blocks the inhibitory effect of GABA on the firing of DA neurons.
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