Present address: Brain Research Unit, Low Temperature Laboratory, Aalto University School of Science and Technology, Espoo, Finland.
Differing causal roles for lateral occipital cortex and occipital face area in invariant shape recognition
Article first published online: 28 JUN 2010
© The Authors (2010). Journal Compilation © Federation of European Neuroscience Societies and Blackwell Publishing Ltd
European Journal of Neuroscience
Volume 32, Issue 1, pages 165–171, July 2010
How to Cite
Silvanto, J., Schwarzkopf, D. S., Gilaie-Dotan, S. and Rees, G. (2010), Differing causal roles for lateral occipital cortex and occipital face area in invariant shape recognition. European Journal of Neuroscience, 32: 165–171. doi: 10.1111/j.1460-9568.2010.07278.x
- Issue published online: 6 JUL 2010
- Article first published online: 28 JUN 2010
- Received 21 February 2010, revised 8 April 2010, accepted 13 April 2010
- extrastriate visual cortex;
- rotation invariance;
- state-dependent transcranial magnetic stimulation
The human extrastriate visual cortex contains functionally distinct regions where neuronal populations exhibit signals that are selective for objects. How such regions might play a causal role in underpinning our ability to recognize objects across different viewpoints remains uncertain. Here, we tested whether two extrastriate areas, the lateral occipital (LO) region and occipital face area (OFA), contained neuronal populations that play a causal role in recognizing two-dimensional shapes across different rotations. We used visual priming to modulate the rotation-sensitive activity of neuronal populations in these areas. State-dependent transcranial magnetic stimulation (TMS) was applied after the presentation of a shape and immediately before a subsequent probe shape to which participants had to respond. We found that TMS applied to both the LO region and OFA modulated rotation-invariant shape priming but, whereas the LO region was modulated by TMS for small rotations, the OFA was modulated for larger rotations. Importantly, our results demonstrate that a node in the face-sensitive network, the OFA, participates in causally relevant encoding of non-face stimuli.