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Fig. S1. CsCl and ZD7288 (ZD) show a similar effect on coincidence detection. (A) Voltage responses to the coincidence detection protocol in control conditions and in the presence of 1 mm CsCl in the bath. (B) Percentage of cells that fired APs in response to the current pulse/EPSP stimulation at different lags in control conditions (black bars) and in the presence of CsCl (white bars). (C) Voltage responses to the coincidence detection protocol at 35 °C in control conditions and in the presence of ZD. Percentage of cells that fired APs in response to the current pulse/EPSP stimulation at different lags at 35 °C (black bars, control; white bars, ZD). *< 0.05, Z-test.

Fig. S2. HCN1 and HCN4 are expressed across the LSO with no medio-lateral gradient. HCN1 (left) and HCN4 (right) expression across the LSO of two normal mice (CBA). L, lateral.

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