SEARCH

SEARCH BY CITATION

Fig. S1. Representative coronal sections of sham and 6-OHDA-lesioned animals 24 h after manganese injection. 3D-T1 weighted images acquired with MDEFT sequence. See Materials and methods for details.

Fig. S2. Immunohistochemical evaluation of STN integrity after MnC12 injection. Representative NeuN immunohistochemistry in the STN from 14-mm coronal section of MnC12-injected and non-injected hemisphere. The subthalamic nucleus (STN) is pointed with an arrow. Images were obtained with an optical microscope using ×40 magnification.

Table S1 Averages oFFractional Anisotropy, Apparent Diffusion Coefficient, Axial and Radial Diffusivities calculated for different ROIs in the ipsilateral and contralateral hemispheres oFsham-operated and 6-OHDA-operated animals at the pre-lesion scan and 3 and 14 days after the injection. Data is expressed as mean ± standard deviation. *indicates significant differences vs. sham, dollar symbol indicates significant differences vs. pre-lesion measuremnts, T indicates differences vs hemispheres P < 0.05.

Table S2 Multiple ANOVAs for diffusion tensor imaging coefficient changes induced by 6-OHDA lesion.

Table S3 Pre-lesion T1 longitudinal relaxation times (ms) of sham- and 6-OHDA-operated animals. Data is expressed as mean ± standard deviation.

As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer-reviewed and may be re-organized for online delivery, but are not copy-edited or typeset by Wiley-Blackwell. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.

FilenameFormatSizeDescription
EJN_7639_sm_f1.tif271KSupporting info item
EJN_7639_sm_f2.tif526KSupporting info item
EJN_7639_sm_t1-2.doc372KSupporting info item

Please note: Wiley Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.