Fig. S1. Basal pERK1/2 levels are unaltered in several genetic mouse models. Basal levels of striatal pERK1/2 were compared from drug-naive wild-type (WT) littermates and either D2 receptor (D2R) KO (A), DAT KO (B), β-arrestin (βarr)-2 KO (C) or β-arrestin-1 KO (D) mice. Representative western blots and the corresponding densitometric analyses are shown. Data are mean + SEM; = 5 mice for each treatment group. No significant differences were found between genotypes by unpaired t-test.

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