Interactions of odorants with olfactory receptors and receptor neurons match the perceptual dynamics observed for woody and fruity odorant mixtures
Version of Record online: 6 FEB 2012
© 2012 The Authors. European Journal of Neuroscience © 2012 Federation of European Neuroscience Societies and Blackwell Publishing Ltd
European Journal of Neuroscience
Volume 35, Issue 4, pages 584–597, February 2012
How to Cite
Chaput, M. A., El Mountassir, F., Atanasova, B., Thomas-Danguin, T., Le Bon, A. M., Perrut, A., Ferry, B. and Duchamp-Viret, P. (2012), Interactions of odorants with olfactory receptors and receptor neurons match the perceptual dynamics observed for woody and fruity odorant mixtures. European Journal of Neuroscience, 35: 584–597. doi: 10.1111/j.1460-9568.2011.07976.x
- Issue online: 14 FEB 2012
- Version of Record online: 6 FEB 2012
- Received 1 March 2011, accepted 1 December 2011
Fig. S1. The concentration–response profiles of OR1G1- and OR52D1-expressing HEK293T cells to ISO (grey bars) and WL (black bars). Ca2+ responses were recorded over 3 min and were reported as the percentage of responding cells normalised to those responding to 100 μm ATP. Both ISO and WL activated the receptors in a concentration-dependent manner.
Fig. S2. The concentration–response curves of unitary ORN responses to ISO and ISO-WL mixtures, demonstrating a concentration tuning for WL and ISO. WL was clearly encoded over its entire concentration range when it was delivered singly, whereas ISO dominated in the mixtures.
Fig. S3. The concentration–response curves of unitary ORN responses to ISO delivered alone or in a mixture. These ORNs were completely non-responsive to WL.
Fig. S4. The mean of the individual perceived intensity of ISO or WL (at different concentrations) when delivered alone.
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