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Table S1 Trait values for 49 Asclepias and 2 Gomphocarpus milkweed species.

Table S2 Estimated phylogenetic signal for shoot and root cardenolide related traits.

Table S3 Phylogenetic analyses of cardenolide traits against average Asclepias spp. latitudinal distribution.

Table S4 Pairwise interactions between cardenolide-related traits.

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