Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity
Article first published online: 1 APR 2009
© 2009 Society for Applied Microbiology and Blackwell Publishing Ltd
Volume 11, Issue 8, pages 1959–1970, August 2009
How to Cite
Le Roux, F., Zouine, M., Chakroun, N., Binesse, J., Saulnier, D., Bouchier, C., Zidane, N., Ma, L., Rusniok, C., Lajus, A., Buchrieser, C., Médigue, C., Polz, M. F. and Mazel, D. (2009), Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity. Environmental Microbiology, 11: 1959–1970. doi: 10.1111/j.1462-2920.2009.01918.x
- Issue published online: 3 AUG 2009
- Article first published online: 1 APR 2009
- Received 10 December, 2008; accepted 22 February, 2009.
Vibrio splendidus is a dominant Vibrio species in seawater presenting a remarkable genetic diversity; several strains have been linked to invertebrate's mortality. We report the complete genome sequence of V. splendidus LGP32, an oyster pathogen, and its comparison with partial genome sequences from related strains. As is typical for the genus, V. splendidus LGP32 contains two chromosomes (3.29 and 1.67 Mb) and most essential cellular processes are encoded by chromosome 1. Comparison with two other V. splendidus partial genome sequences (strains 12B01 and Med222) confirms the previously suggested high genotypic diversity within this species and led to the identification of numerous strain-specific regions that could frequently not be assigned to a specific mechanisms of recombination. Surprisingly, the chromosomal integron, the most variable genetic element in all other Vibrio species analysed to date, is absent from 12B01 and inactivated by a mobile element in Med222, while in LGP32 it only contains a limited number of cassettes. Finally, we found that the LGP32 integron contains a new dfrA cassette, related to those found in resistance integrons of Gram-negative clinical isolates. Those results suggest that marine Vibrio can be a source of antibiotic resistance genes.