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Fig. S1. Proposed Entner–Doudoroff pathway found in some members of the SAR11 clade. Gene names are for HTCC1062.

Table S1. Comparison of central metabolism in SAR11 isolates HTCC1002, HTCC1062 and HTCC7211. Due to predicted lesions in pentose phosphate shunt, reactions yielding NADPH are indicated with a ‘NADPH’.

Table S2. Transcription profile of HTCC1062 when grown using glucose as the primary carbon source compared with No Carbon control treatments. Positive (glucose) or negative (No Carbon) fold-change values indicate carbon source on which transcription was greater. Most highly detected transcripts are also shown. Genes in the SAR11 ED operon are indicated in bold.

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