Supporting information S1. Sequences distribution (in percentage) across the various genera embedded in the assembled data set. Only those genera possessing at least the 0.5% of the overall data set are reported.

Supporting information S2. The entire, Visone-formatted, network of antibiotic resistance-related sequences obtained as described in Experimental procedures.

Supporting information S3. Degree distribution at different WIV thresholds.

Supporting information S4. In-depth analysis of the TetA, CAT and AphA sequences subnetworks.

Supporting information S5. The list of the 95 highly interconnected nodes exhibiting more than 30 links.

Supporting information S6. Betweenness calculation for all the nodes composing in the network.

Supporting information S7. All the antibiotic resistance-related sequences used in this analysis.

EMI_2295_sm_Rev.zip3265KSupporting info item

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