New roles for bacterial siderophores in metal transport and tolerance
Article first published online: 30 AUG 2011
© 2011 Society for Applied Microbiology and Blackwell Publishing Ltd
Volume 13, Issue 11, pages 2844–2854, November 2011
How to Cite
Schalk, I. J., Hannauer, M. and Braud, A. (2011), New roles for bacterial siderophores in metal transport and tolerance. Environmental Microbiology, 13: 2844–2854. doi: 10.1111/j.1462-2920.2011.02556.x
- Issue published online: 31 OCT 2011
- Article first published online: 30 AUG 2011
- Received 13 May, 2011; accepted 21 June, 2011.
Siderophores are chelators with extremely strong affinity for ferric iron and are best known for their capacity to feed microorganisms with this metal. Despite their preference for iron, they can also chelate numerous other metals with variable affinities. There is also increasing evidence that metals other than iron can activate the production of siderophores by bacteria, thereby implicating siderophores in the homeostasis of metals other than iron and especially heavy metal tolerance. This article considers this new concept that siderophores play a role in protecting bacteria against metal toxicity and discusses the possible contribution of these chelators to the transport of biological relevant metals in addition to iron.