Beyond the Venn diagram: the hunt for a core microbiome
Article first published online: 17 OCT 2011
© 2011 Society for Applied Microbiology and Blackwell Publishing Ltd
Special Issue: OMICS Driven Microbial Ecology
Volume 14, Issue 1, pages 4–12, January 2012
How to Cite
Shade, A. and Handelsman, J. (2012), Beyond the Venn diagram: the hunt for a core microbiome. Environmental Microbiology, 14: 4–12. doi: 10.1111/j.1462-2920.2011.02585.x
- Issue published online: 2 JAN 2012
- Article first published online: 17 OCT 2011
- Received 22 April, 2011; accepted 5 August, 2011.
Discovering a core microbiome is important for understanding the stable, consistent components across complex microbial assemblages. A core is typically defined as the suite of members shared among microbial consortia from similar habitats, and is represented by the overlapping areas of circles in Venn diagrams, in which each circle contains the membership of the sample or habitats being compared. Ecological insight into core microbiomes can be enriched by 'omics approaches that assess gene expression, thereby extending the concept of the core beyond taxonomically defined membership to community function and behaviour. Parameters defined by traditional ecology theory, such as composition, phylogeny, persistence and connectivity, will also create a more complex portrait of the core microbiome and advance understanding of the role of key microorganisms and functions within and across ecosystems.