Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells
Article first published online: 27 JAN 2006
Volume 8, Issue 3, pages 375–386, March 2006
How to Cite
Ludwig, S., Pleschka, S., Planz, O. and Wolff, T. (2006), Ringing the alarm bells: signalling and apoptosis in influenza virus infected cells. Cellular Microbiology, 8: 375–386. doi: 10.1111/j.1462-5822.2005.00678.x
- Issue published online: 27 JAN 2006
- Article first published online: 27 JAN 2006
- Received 2 November, 2005; accepted 30 November, 2005.
Small RNA viruses such as influenza viruses extensively manipulate host-cell functions to support their replication. At the same time the infected cell induces an array of defence mechanisms to fight the invader. These processes are mediated by a variety of intracellular signalling cascades. Here we will review the current knowledge of functional kinase signalling and apoptotic events in influenza virus infected cells and how these viruses have learned to misuse these cellular responses for efficient replication.