A concerted action of HNF4α and HNF1α links hepatitis B virus replication to hepatocyte differentiation
Article first published online: 11 MAR 2008
© 2008 The Authors. Journal compilation © 2008 Blackwell Publishing Ltd
Volume 10, Issue 7, pages 1478–1490, July 2008
How to Cite
Quasdorff, M., Hösel, M., Odenthal, M., Zedler, U., Bohne, F., Gripon, P., Dienes, H.-P., Drebber, U., Stippel, D., Goeser, T. and Protzer, U. (2008), A concerted action of HNF4α and HNF1α links hepatitis B virus replication to hepatocyte differentiation. Cellular Microbiology, 10: 1478–1490. doi: 10.1111/j.1462-5822.2008.01141.x
- Issue published online: 11 MAR 2008
- Article first published online: 11 MAR 2008
- Received 3 December, 2007; revised 6 February, 2008; accepted 24 February, 2008.
Fig. S1. Differentiation markers in stably HBV-producing cell lines. Stably HBV-producing cell lines HepG2 2.15 (left) and HepG2-H1.3 (right) were cultured under differentiating conditions and lysed at indicated time points. OATP-C and BSEP mRNA was determined relative to GAPDH by LightCycler™ real-time RT-PCR. The normalized expression level at day 0 was set to 1 (in HepG2 2.15 cells, OATP-C mRNA at day 0 was undetectable). Representative experiment is shown.
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