Elective sigmoid colectomy for diverticular disease. Laparoscopic vs open surgery: a systematic review
Article first published online: 9 MAY 2012
© 2011 The Authors. Colorectal Disease © 2011 The Association of Coloproctology of Great Britain and Ireland
Volume 14, Issue 6, pages 671–683, June 2012
How to Cite
Cirocchi, R., Farinella, E., Trastulli, S., Sciannameo, F. and Audisio, R. A. (2012), Elective sigmoid colectomy for diverticular disease. Laparoscopic vs open surgery: a systematic review. Colorectal Disease, 14: 671–683. doi: 10.1111/j.1463-1318.2011.02666.x
- Issue published online: 9 MAY 2012
- Article first published online: 9 MAY 2012
- Accepted manuscript online: 16 MAY 2011 02:34PM EST
- Received 31 August 2010; accepted 10 December 2010; Accepted Article online 16 May 2011
- Diverticular disease;
- elective treatment
Aim A meta-analysis of nonrandomized studies and one randomized trial was conducted to compare laparoscopic surgery with open surgery in the elective treatment of patients with diverticular disease.
Method Published randomized and controlled clinical trials that directly compared elective open (OSR) with laparoscopic surgical resection (LSR) in patients with diverticular disease were identified using the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE and EMBASE. End-points included 30-day mortality and morbidity and were compared by determining the relative risk ratio, odds ratio, and the absolute effects.
Results Eleven nonrandomized studies of 1430 patients were identified and included in the meta-analysis. There was only one randomized study, which included 104 patients. The meta-analysis suggested that elective LSR was a safe and appropriate option for patients with diverticular disease and was associated with lower overall morbidity (P = 0.01) and minor complication rate (P = 0.008).
Conclusion The results of the nonrandomized study generally agreed with those of the randomized study, except for the incidence of minor complications, which was higher in both the LSR and OSR groups of the randomized study. In this study, the high overall morbidity of 42.3% reported in the LSR group is a cause for concern.