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Benefits of moderate weight loss in patients with type 2 diabetes
Article first published online: 22 SEP 2009
DOI: 10.1111/j.1463-1326.2009.01155.x
© 2010 Blackwell Publishing Ltd
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How to Cite
Fujioka, K. (2010), Benefits of moderate weight loss in patients with type 2 diabetes. Diabetes, Obesity and Metabolism, 12: 186–194. doi: 10.1111/j.1463-1326.2009.01155.x
Publication History
- Issue published online: 31 JAN 2010
- Article first published online: 22 SEP 2009
- Date submitted 22 May 2009; date of first decision 7 July 2009; date of final acceptance 12 August 2009
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Keywords:
- blood glucose;
- diabetes mellitus;
- diabetes mellitus - type 2;
- outcome assessment;
- risk assessment;
- therapeutics;
- weight gain;
- weight loss;
- weight-loss agents
Weight loss is a primary goal of therapy in overweight patients with type 2 diabetes. This review examines whether positive patient outcomes are observed even after relatively small amounts of weight loss, that is, weight loss being more easily attainable in practice. Clinical studies demonstrate that therapeutic benefit rises with increasing weight loss, but that losses as low as 0.45–4 kg (1–9 lb) have positive effects on metabolic control, cardiovascular risk factors and mortality rates. Even the intention to lose weight, without significant success, can improve outcomes in patients with diabetes, presumably because of the healthy behaviours associated with the attempt. The current data support a continued focus on weight loss, including moderate weight loss, as a key component of good care for overweight patients with type 2 diabetes.