Suspected ivermectin toxicosis in a miniature mule foal causing blindness

Authors

  • Caryn E. Plummer,

    1. Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610–0126, USA
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  • Maria E. Kallberg,

    1. Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610–0126, USA
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  • Franck J. Ollivier,

    1. Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610–0126, USA
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  • Dennis E. Brooks,

    1. Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610–0126, USA
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  • Kirk N. Gelatt

    1. Departments of Small and Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610–0126, USA
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Address communications to: M. E. Kallberg Tel.: (352) 392 4700 Fax: (352) 392 6125 e-mail: kallbergm@mail.vetmed.ufl.edu

Abstract

A 9-week-old miniature mule foal presented to the Veterinary Medical Teaching Hospital for acute blindness, ataxia, and depression following an overdose of an over-the-counter ivermectin-based de-worming medication. Ophthalmic examination and electrodiagnostic evaluation eliminated outer retinal abnormalities as the primary cause of the bilateral blindness, implicating instead a central neurologic effect of the drug. With symptomatic and supportive care, the foal recovered fully and regained its vision.

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