Get access

Eosinophilic keratoconjunctivitis in two rabbits

Authors

  • Petra Grinninger,

    1. Ophthalmology section, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Search for more papers by this author
  • Rick Sanchez,

    1. NKR Veterinary Specialists, 36 Warren Road, Blue Bell Hill, Kent ME5 9RD, UK
    Search for more papers by this author
  • Ingrid M. G. Kraijer-Huver,

    1. Ophthalmology section, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Search for more papers by this author
  • Willem-Jan P. Kitslaar,

    1. Division of Zoological Medicine, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Search for more papers by this author
  • Nico J. Schoemaker,

    1. Division of Zoological Medicine, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Search for more papers by this author
  • Guy C. M. Grinwis,

    1. Division of Pathology, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Search for more papers by this author
  • Michael H. Boevé

    1. Ophthalmology section, Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, The Netherlands
    Search for more papers by this author

Address communications to:
P. Grinninger
Tel.: +31-30-253-9697
Fax: +31-30-253-9393
e-mail: p.grinninger@uu.nl

Abstract

The purpose of this case report is to describe the clinical course and cytologic findings, treatment, and outcome of eosinophilic keratoconjunctivitis in two rabbits. Ophthalmic examination revealed ocular discharge, dacryocystitis, blepharitis, conjunctivitis, white conjunctival and corneal plaques, corneal vascularization, and stromal infiltration with different degrees of severity in each case. In case 2 there was also ulcerative disease of the cornea. Computerized tomography scan of the head, corneal biopsy for histopathologic examination with additional Luna and Giemsa stain were performed in case 2 and conjunctival as well as corneal specimens were obtained for bacteriologic culture and cytologic examination in case 1. Based on test results, a diagnosis of eosinophilic keratoconjunctivitis was made in case 2 and a tentative diagnosis of eosinophilic keratoconjunctivitis was made in case 1. Response to treatment with a topical steroid and topical cyclosporin was supportive of the diagnosis in both cases and shared many similarities with the response to treatment previously described in cats. Eosinophilic keratitis should be considered as part of a differential diagnosis list in rabbits with a history of keratitis.

Ancillary