‡Present address: Klinika za male živali, Gorkičeva 6, SI-1000 Ljubljana, Slovenia.
Clinical ocular findings in cows with malignant catarrhal fever: ocular disease progression and outcome in 25 cases (2007–2010)
Article first published online: 12 JUL 2011
© 2011 American College of Veterinary Ophthalmologists
Volume 15, Issue 1, pages 46–52, January 2012
How to Cite
Zemljič, T., Pot, S. A., Haessig, M. and Spiess, B. M. (2012), Clinical ocular findings in cows with malignant catarrhal fever: ocular disease progression and outcome in 25 cases (2007–2010). Veterinary Ophthalmology, 15: 46–52. doi: 10.1111/j.1463-5224.2011.00925.x
- Issue published online: 18 JAN 2012
- Article first published online: 12 JUL 2011
- anterior uveitis;
- corneal edema;
- malignant catarrhal fever;
- ovine herpes virus 2;
- prognostic indicator
Objective To describe the ocular clinical signs in a group of cows diagnosed with sheep associated malignant catarrhal fever (MCF), and to investigate a possible correlation between the severity and progression of certain typical clinical signs and disease outcome.
Procedure This prospective study involved cows diagnosed with MCF between 2007 and 2010, and included cows enrolled in a larger clinical trial. Signalment of affected cows, presence and progression of ocular lesions, as well as disease outcome were recorded. Cows were divided into two groups based on the disease outcome: (1) survival and (2) nonsurvival. The degree of corneal edema at first examination was statistically compared between groups. The progression of corneal edema, uveitis and the examining ophthalmologists’ subjective assessment of disease progression between the first and last examination were also compared between groups.
Results Twenty-five cows (22 F, 3 M) of six different breeds and one mixed breed were included. Median age was 21 months (range 8–113). Ten cows survived, 13 cows were euthanized, and two died. No statistical association was identified between the degree of corneal edema at the first examination and the disease outcome. Deterioration of corneal edema was not noticed in any of the surviving animals. Anterior uveitis improved in all 10 surviving cows.
Conclusions The degree of corneal edema at first examination had no prognostic value for the disease outcome. The results of this study suggest that the progression of corneal edema correlates well with disease outcome, and that nonimprovement of uveitis is a bad prognostic sign.