Effect of topical anesthesia on evaluation of corneal sensitivity and intraocular pressure in rats and dogs
Version of Record online: 23 APR 2012
© 2012 American College of Veterinary Ophthalmologists
Volume 16, Issue 1, pages 43–46, January 2013
How to Cite
Kim, J., Kim, N.-S., Lee, K.-C., Lee, H.-B., Kim, M.-S. and Kim, H.-S. (2013), Effect of topical anesthesia on evaluation of corneal sensitivity and intraocular pressure in rats and dogs. Veterinary Ophthalmology, 16: 43–46. doi: 10.1111/j.1463-5224.2012.01020.x
- Issue online: 7 JAN 2013
- Version of Record online: 23 APR 2012
- corneal touch threshold;
- intraocular pressure;
Objective To determine the effect of 0.5% proparacaine in tonometry by evaluating corneal touch threshold (CTT) and intraocular pressure (IOP).
Animal studied Nine rats (18 eyes, Sprague–Dawley) and 10 dogs (20 eyes, Beagle)
Procedures The IOP and CTT were measured in each eye before and after topical anesthesia with 0.5% proparacaine. The IOP was evaluated using Tonopen for dogs and Tonolab for rats. The corneal sensitivity was evaluated by CTT through a Cochet–Bonnet aesthesiometer.
Results The mean IOP was not significantly changed in rats or dogs before and after topical anesthesia. However, after application of proparacaine, CTT was significantly increased in both animal groups compared with that before application of proparacaine.
Conclusion From this study, topical anesthesia was found to significantly lower the corneal sensitivity but have little effect on IOP measurements. In ophthalmologic examination, topical anesthesia can be used to reduce corneal sensation without an effect on IOP.