Correlation between corneal sensitivity and quantity of reflex tearing in cows, horses, goats, sheep, dogs, cats, rabbits, and guinea pigs
Article first published online: 15 OCT 2012
© 2012 American College of Veterinary Ophthalmologists
Volume 16, Issue 4, pages 251–262, July 2013
How to Cite
Wieser, B., Tichy, A. and Nell, B. (2013), Correlation between corneal sensitivity and quantity of reflex tearing in cows, horses, goats, sheep, dogs, cats, rabbits, and guinea pigs. Veterinary Ophthalmology, 16: 251–262. doi: 10.1111/j.1463-5224.2012.01069.x
- Issue published online: 5 JUL 2013
- Article first published online: 15 OCT 2012
- corneal touch threshold;
- palpebral fissure length;
- Schirmer tear test;
- tear film
Objective Guinea pigs have a very low threshold of corneal sensitivity and at the same time nearly no reflex tearing compared to dogs, cats, and horses. The question arose whether there is a general correlation between corneal sensitivity and the quantity of reflex tearing.
Animals studied Totally 160 animals of 8 different species (20 animals per species) were investigated.
Procedures The corneal touch threshold (CTT) was measured with a Cochet–Bonnet esthesiometer. The palpebral fissure length (PFL) was measured with a calliper ruler. The Schirmer tear test (STT) was modified by adapting the width of the STT strip to the PFL of every species. For the STT II, 0.4% oxybuprocaine was applied.
Results Corneal touch threshold: Cows (1.67 g/mm2), horses (1.23 g/mm2), sheep (1.13 g/mm2), goats (1.44 g/mm2), dogs (2.16 g/mm2), and cats (1.33 g/mm2) show similar CTT values. In contrast, rabbits (6.21 g/mm2) and guinea pigs (7.75 g/mm2) show a significantly lower CTT. Tear Production Difference STT I − STT II: Rabbits have the greatest decline in tear production with 38.4%, followed by sheep (33.3%), dogs (31.1%), cats (24.7%), cows (23.7%), horses (18.0%), and goats (14.0%). Guinea pigs have no decline, but a slight increase of −16.0%. Correlation CTT and STT II − STT I Difference: Pearson’s correlation coefficient shows a small, but significant correlation. The coefficient of determination can only forecast a value with 7.1% certainty.
Conclusions The high variance and low reproducibility of results suggest that the measuring devices are inappropriate to assess the evaluated parameters. Therefore, no assured correlation between the corneal sensitivity and the quantity of reflex tearing could be found.