Half-body Irradiation in the Treatment of Metastatic Prostatic Carcinoma
Article first published online: 21 NOV 2008
British Journal of Urology
Volume 53, Issue 6, pages 628–629, December 1981
How to Cite
ROWLAND, C. G., BULLIMORE, J. A., SMITH, P. J. B. and ROBERTS, J. B. M. (1981), Half-body Irradiation in the Treatment of Metastatic Prostatic Carcinoma. British Journal of Urology, 53: 628–629. doi: 10.1111/j.1464-410X.1981.tb03277.x
- Issue published online: 21 NOV 2008
- Article first published online: 21 NOV 2008
Summary-High dose radiation therapy given as a single fraction to the upper and lower halves of the body gives effective palliation for metastatic solid tumours. This treatment modality appears to be particularly effective in tumours which may have a slow doubling time such as carcinoma of the prostate.
Fifty-two patients with metastatic carcinoma of the prostate involving the skeletal system have received half-body irradiation. All had prior treatment with additive hormones or orchiectomy and the majority had received localised irradiation and/or chemotherapy. Significant immediate pain relief was achieved in 42 out of 52 patients (80%). This pain relief was maintained until death in 29 out of 43 patients (67%). Pain relief in responders appears to occur within 24 to 48 h of treatment.