Ta and T1 Bladder Cancer: Location, Recurrence and Progression

Authors

  • N. M. HENEY,

    Corresponding author
    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      N. M. Heney, MD, FRCSI, FRCS, Assistant Professor of Surgery, Harvard Medical School; Associate Urologist, Massachusetts General Hospital.

  • B. N. NOCKS,

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      B. N. Nocks, MD, Assistant Professor of Surgery, Harvard Medical School; Assistant Urologist, Massachusetts General Hospital.

  • J. J. DALY,

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      J. J. Daly, MB.BCh, BAO, MSc(Path), Assistant Clinical Professor of Pathology, Harvard Medical School; Clinical Associate in Pathology, Massachusetts General Hospital.

  • G. R. PROUT JR.,

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      G. R. Prout, Jr, MD, FACS, Professor of Surgery, Harvard Medical School; Chief of the Urological Service, Massachusetts General Hospital.

  • J. B. NEWALL,

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      J. B. Newall, Director of Medical Research Applications, Harvard University, Cambridge.

  • PAMELA P. GRIFFIN,

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      Pamela P. Griffin, RN, Nurse Clinician, Massachusetts General Hospital.

  • THERESA L. PERRONE,

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      Theresa L. Perrone, MD, Resident in Pathology, Massachusetts General Hospital.

  • WANDA A. SZYFELBEIN

    1. Urological Service, Departments of Surgery and Pathology and Cardiac Unit, Massachusetts General Hospital, Harvard Medical School, Boston, USA
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      Wanda A. Szyfelbein, MD, Instructor in Pathology, Harvard Medical School; Assistant Pathologist, Massachusetts General Hospital.


  • Read at the Annual Meeting of the American Urological Association, San Francisco, May 1980.

  • Read at the Annual Meeting of the American Urological Association, San Francisco, May 1980.

Urological Service, Massachusetts General Hospital, Fruit Street, Boston, Massachusetts 02114, USA.

Abstract

Summary— An analysis of 58 patients who presented with their first superficial bladder tumour(s) stage Ta or T1 and who were followed prospectively is presented. Tumour characteristics which correlated well with the likelihood of new tumour occurrence were invasion of lamina propria, multiplicity, size equal to or greater than 3 cm and abnormal selected mucosal biopsies. Positive urinary cytology and higher grade tumours correlated, though less strongly. Development of higher grade or stage in subsequent tumours (i.e. progression) was associated with initial tumour multiplicity. While initial tumours were rarely found on the dome (5.2%), new tumour occurrences involved the dome in 29% of patients.

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