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M. I. Frazer, MD, MRCOG, First Assistant, University Department of Obstetrics and Gynaecology, Newcastle General Hospital, Newcastle upon Tyne.
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Do Women with Idiopathic Sensory Urgency have Early Interstitial Cystitis?
Article first published online: 26 NOV 2008
DOI: 10.1111/j.1464-410X.1990.tb14925.x
© 1990 British Journal of Urology
Additional Information
How to Cite
FRAZER, M. I., HAYLEN, B. T. and SISSONS, M. (1990), Do Women with Idiopathic Sensory Urgency have Early Interstitial Cystitis?. British Journal of Urology, 66: 274–278. doi: 10.1111/j.1464-410X.1990.tb14925.x
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M. I. Frazer, MD, MRCOG, First Assistant, University Department of Obstetrics and Gynaecology, Newcastle General Hospital, Newcastle upon Tyne.
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B. T. Haylen, MD, MRCOG, FRACOG, Specialist Obstetrician and Gynaecologist, St Margaret's Hospital, Sydney, Australia
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M. Sissons, MD, MRCPath, Consultant Pathologist, Blackpool General Hospital, Blackpool.
Publication History
- Issue published online: 26 NOV 2008
- Article first published online: 26 NOV 2008
- Accepted for publication 29 January 1990
- Abstract
- References
- Cited By
Summary— Interstitial cystitis is rarely considered as a cause of urinary symptoms in referrals to gynaecology clinics. Recent concepts in the diagnosis of this condition mean that it is emerging as a much more common entity, with both early and late forms of the disease being described. Mast cell density in the detrusor muscle has been reported to be useful as a disease marker to substantiate the diagnosis of interstitial cystitis where no classical diagnostic features exist. We assessed mast cell counts in bladder biopsies from 27 women with idiopathic sensory urgency and 10 control patients about to undergo a colposuspension procedure for pure genuine stress incontinence; 30% of the study group had a clear increase in the detrusor muscle mast cell population (detrusor mastocytosis). No control patient showed such an increase. Early interstitial cystitis should be considered as a possible cause of lower urinary tract symptoms in patients with apparently idiopathic sensory urgency.